Microsoft Word - 87524580-file00

1 Genetics Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 2 National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham, MA 3 Division of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston, Department of Pathology, Beth Israel Deaconess Hospital, Harvard Medical School Harvard Stem Cell Institute, Cambridge, MA 6 Gastroenterology Division, Brigham and Women’s Hospital; Gastrointestinal Cancer Center, Dana-Farber Cancer Institute, Boston, MA